Chromosomal Studies in Erythroleukemia and Chronic Erythremic Myelosis

Arginine methyltransferase activity in chronic erythremic myelosis (Diguglielmo syndrome).

Activity of S-adenosylmethionine-dependent arginine methyltransferase was substantially higher in sonicated bone marrow samples from 6 patients with chronic erythremic myelosis than in bone marrow from 3 patients with untreated pernicious anemia, 2 patients with autoimmune hemolytic anemia, and 4 normal persons. Increased activity of this enzyme may be one of the factors contributing to the pat...

5-Methyltetrahydrofolate-dependent methyltransferase activity in chronic erythremic myelosis and other types of anemias.

Uiromosomal Studies in Erythroleukemia and Chronic

T HE DI GUGLIELMO SYNDROME1 is a condition characterized principally by neoplastic proliferation of the cells of the erythroid series, which is frequently, if not invariably, associated with leukemic proliferation of the cells of the granulocytic series. It is usually of acute variety but-rarely-chronic forms are encountered. The term “acute erythremic myelosis” or “Di Guglielmo disease”2 is fr...

Acute erythremic myelosis (true erythroleukaemia): a variant of AML FAB-M6.

AIMS Classic erythroleukaemia (acute myeloid leukaemia M6, or M6 AML) is defined as an excess of myeloblasts in an erythroid predominant background. Leukaemia variants in which the primitive blast cells are demonstrably erythroid are extremely rare and poorly characterised. Variably referred to as "true erythroleukaemia" or "acute erythremic myelosis", they are often included within the M6 AML ...

Chronic myelosis following the use of thorotrast.

EPORTS have recently beemi appearimig imi the world literature, point.imig out the late deleterious effects of thorotrast, which has been used since 1930, especially for hepatohienography. The majority of these communications lay stress on the toxic effect of the radioactive material emitted by thorotrast. and warn against its further use ; many authors emphasize in particular the carcinogenic ...